Trandolaprilum [Latin]
Brand names,
Trandolaprilum [Latin]
Analogs
Trandolaprilum [Latin]
Brand Names Mixture
Trandolaprilum [Latin]
Chemical_Formula
C20H27NO3
Trandolaprilum [Latin]
RX_link
No information avaliable
Trandolaprilum [Latin]
fda sheet
Trandolaprilum [Latin]
msds (material safety sheet)
Trandolaprilum [Latin]
Synthesis Reference
No information avaliable
Trandolaprilum [Latin]
Molecular Weight
329.433 g/mol
Trandolaprilum [Latin]
Melting Point
264 oC
Trandolaprilum [Latin]
H2O Solubility
No information avaliable
Trandolaprilum [Latin]
State
Solid
Trandolaprilum [Latin]
LogP
2.635
Trandolaprilum [Latin]
Dosage Forms
Capsules
Trandolaprilum [Latin]
Indication
Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trandolaprilum [Latin]
Pharmacology
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland. This product was withdrawn from the U.S. market in April 1994.
Trandolaprilum [Latin]
Absorption
No information avaliable
Trandolaprilum [Latin]
side effects and Toxicity
Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
Trandolaprilum [Latin]
Patient Information
No information avaliable
Trandolaprilum [Latin]
Organisms Affected
Humans and other mammals